NSIDRC Journal Article Alert — June 18, 2010
Prepared by the National Sudden and Unexpected Infant/Child Death and Pregnancy Loss Resource Center at Georgetown University.
These articles have been selected from PubMed, a service of the National Library of Medicine that includes over 19 million citations from MEDLINE and other life science journals for biomedical articles back to 1948. PubMed includes links to full text articles and other related resources.
Availability of full-text journal articles is often limited to subscribers or through inter-library loan. Please see your local library for copies of these articles, or view PubMed's How to Get the Journal Article or Partners in Information Access for the Public Health Workforce's How to Access Journal Articles for more details.
Sudden Infant Death
1. Kadhim H, Deltenre P, De Prez C, Sébire G
Interleukin-2 as a Neuromodulator Possibly Implicated in the
Physiopathology of Sudden Infant Death Syndrome
Neurosci Lett. 2010 Jun 10. [Epub ahead of print]
Neuropathology Unit, Department of Anatomic Pathology and
Clinical Biology, Centre Hospitalier Universitaire BRUGMANN,
Université Libre de Bruxelles (U.L.B.), Brussels, BELGIUM.
Abstract
Dysfunction in vital brainstem centers, including those controlling
cardiorespiratory- and sleep/arousal pathophysiology, is reported
in sudden infant death syndrome (SIDS). Biological mechanisms
underlying SIDS, however, remain unclear. Cytokines are intercellular
signaling chemicals. They can interact with neurotransmitters
and might thus modify neural and neuroimmune functions. Cytokines
could therefore act as neuromodulators. Interleukin (IL)-2
is a major immune-related cytokine. It has not been previously
depicted in vital brainstem centers. We detected intense neuronal
IL-2 immune-reactivity in the SIDS brainstem, namely in vital
neural centers. This IL-2 overexpression might interfere with
neurotransmitters in those critical brainstem centers, causing
disturbed homeostatic control of cardiorespiratory and arousal
responses, possibly leading to SIDS. Copyright © 2010. Published
by Elsevier Ireland Ltd.
Miscarriage/Stillbirth/Prenatal Issues
1. Houston M.
Ireland is to review accuracy of its miscarriage diagnoses
to avoid damaging interventions
BMJ 2010 Jun 15:340:c3203 doi: 10.1136/bmj.c3203
* News
2. Woods-Giscombé CL, Lobel M, Crandell JL
The impact of miscarriage and parity on patterns of maternal
distress in pregnancy
Res Nurs Health. 2010 Jun 11. [Epub ahead of print]
School of Nursing, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
The purpose of the current study was to examine patterns of state anxiety and pregnancy-specific distress across pregnancy in a diverse sample of women with (n = 113) and without (n = 250) prior miscarriage. For both groups, state anxiety and pregnancy-specific distress were highest in the first trimester and decreased significantly over the course of pregnancy. Compared to women without prior miscarriage, women with prior miscarriage experienced greater state anxiety in the second and third trimesters. Having a living child did not buffer state anxiety in women with a prior miscarriage. Attention to patterns of distress can contribute to delivery of appropriate support resources to women experiencing pregnancy after miscarriage and may help reduce risk for stress-related outcomes. (c) 2010 Wiley Periodicals, Inc.
Prepared by the
National Sudden and Unexpected Infant/Child Death and Pregnancy
Loss Resource Center
Georgetown University
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